22:36 , Apr 4, 2018 |  BC Innovations  |  Translation in Brief

New Therapeutic Targets and Biomarkers: March 2018

New Therapeutic Targets and Biomarkers: March 2018 Select top therapeutic targets and biomarkers covered by BioCentury or added to the BCIQ database during March 2018. Therapeutic targets are defined as any protein, gene or other...
16:58 , Mar 22, 2018 |  BC Innovations  |  Distillery Therapeutics

Neurology

INDICATION: Cognitive dysfunction Mouse studies suggest inhibiting ABLIM3 could help treat age-related cognitive dysfunction. In a mouse model of the disease, intrahippocampal injection of ABLIM3-targeting shRNA increased contextual fear memory precision for up to 16...
22:09 , Mar 12, 2018 |  BC Extra  |  Preclinical News

Releasing molecular brake may improve memory recall in PTSD, aging

A study published in Nature Medicine suggests releasing a "molecular brake" between memory stimulating and memory retrieving regions of the hippocampus could offer a new therapeutic strategy to improve memory recall in post-traumatic stress disorder...