07:00 , Sep 6, 2012 |  BC Innovations  |  Targets & Mechanisms

Passenger mutations take the wheel

Two research groups have independently shown that targeting genes carrying passenger mutations blocked growth of cancer cells and improved survival in mouse models. 1,2 Although precise therapeutic windows for such a strategy remain to be...
07:00 , Oct 24, 2011 |  BioCentury  |  Product Development

Alzheimer's rewind

A string of Phase II and III failures in Alzheimer's disease has prompted companies to look for new targets beyond the well-known players in the core mechanism of AD - the production and accumulation of...