02:10 , Dec 8, 2017 |  BC Innovations  |  Targets & Mechanisms

Epiphenomena at ASH

While it’s no surprise that cell therapy research is dominant in hematology, the emergence of epigenetics as an equally large focus at this year’s ASH meeting is more notable, reinforcing the resurgence of a field...
20:34 , Jul 25, 2017 |  BC Innovations  |  Distillery Therapeutics

Pulmonary

INDICATION: Pulmonary Patient sample and mouse studies suggest inhibiting ZBTB7A could help treat lung transplant-associated bronchiolitis obliterans syndrome. In bronchoalveolar lavage samples from lung transplant patients, levels of ZBTB7A were higher in patients who developed...
19:06 , Feb 22, 2017 |  BC Innovations  |  Distillery Techniques

Biomarkers

TECHNOLOGY: SNPs SNPs on nine genomic loci could help predict the risk of CLL. Genome-wide association studies in a total of 4,478 CLL patients and 13,213 healthy volunteers identified associations between the disease and SNPs...
08:00 , Feb 26, 2015 |  BC Innovations  |  Distillery Techniques

Techniques: Mesenchymal stem cell (MSC) screen for oncogenic drivers of undifferentiated sarcomas

Disease models TECHNOLOGY: Cell models An MSC model could help identify therapeutics to treat undifferentiated sarcomas. In isolated MSC-enriched mouse bone marrow cells, p53 depletion plus expression of known sarcoma oncogenes induced sarcomagenesis. In p53-deficient...