19:06 , Feb 21, 2018 |  BC Innovations  |  Distillery Therapeutics

Inflammation

INDICATION: Asthma Mouse studies identified a dithiolo[3,4-c]quinolinylidene-based TAGLN2 agonist that could help treat asthma. Virtual screening of a small molecule library against TAGL2 and chemical synthesis of hits yielded a dithiolo[3,4-c]quinolinylidene analog that bound to...
07:00 , Apr 3, 2014 |  BC Innovations  |  Targets & Mechanisms

Narrowing down graft stenosis

One of the dominant problems after coronary artery bypass graft surgery is hyperplastic growth inside the transplanted blood vessel that can lead to stenosis. Now, a team at the NIH 's National Heart, Lung, and...