19:21 , Jun 20, 2018 |  BC Innovations  |  Distillery Techniques

Biomarkers

TECHNOLOGY: SNPs Seven SNPs on SYNJ1 could help predict outcomes in familial AD. Genome-wide association studies (GWAS) in 305 early-onset and 2,199 late-onset familial AD patients identified four SNPs in SYNJ1 associated with rapid disease...
07:00 , May 1, 2008 |  BC Innovations  |  Cover Story

Cutting the Synaptic Cord

Cutting the Synaptic Cord The earliest steps in Alzheimer's disease have proven tricky to target with therapeutics because they occur as part of normal brain activity and before symptom onset. This pathway now has been...
07:00 , May 1, 2008 |  BC Innovations  |  Distillery Therapeutics

This Week in Therapeutics

This week in therapeutics Indication Target/marker/pathway Summary Licensing status Publication and contact information Neurology Alzheimer's disease (AD) b-amyloid (Ab); phophatidylinositol-4,5-bisphosphate (PIP2) ; synaptojanin 1 (Synj1) Studies in cell culture and mice suggest that antagonizing Synj1...