22:14 , Jun 14, 2019 |  BioCentury  |  Emerging Company Profile

Sherlock: Leveraging CRISPR, synthetic biology for diagnostics

By taking advantage of two hot technologies, Sherlock is developing a pair of molecular diagnostics that can be used alone or together to rapidly and accurately detect disease in a wide variety of applications. Sherlock...
23:42 , May 28, 2019 |  BioCentury  |  Finance

NanoDimension adding European focus for new $335M fund

NanoDimension intends to make its first-ever investments in Europe from its new $335 million third fund, with far more global emphasis on drug development than its previous funds have had. The California-based firm has established...
23:47 , May 23, 2019 |  BC Innovations  |  Tools & Techniques

As polygenic risk scores mature, opportunities emerge for disease interception

With comprehensive genetic risk profiling inching closer to clinical use, the biggest opportunity for drug developers could be the new territory it opens up in disease prevention and interception, particularly for common diseases. Much of...
14:19 , May 14, 2019 |  BC Innovations  |  Distillery Techniques

A circulating tumor cell capture device for cancer diagnosis

TECHNIQUES CATEGORY: Assays and screens TECHNOLOGY: Diagnostic assays An chip-based device for capturing circulating tumor cells (CTCs) could enable more accurate diagnosis of cancer than single-draw liquid biopsies. The device uses a pump and catheters...
19:05 , May 2, 2019 |  BC Innovations  |  Translation in Brief

Continuously capturing cancer cells

A wearable device that captures and isolates circulating tumor cells over the course of a few hours could offer better diagnostic accuracy than single-draw liquid biopsies that screen smaller amounts of blood. A University of...
17:09 , Apr 18, 2019 |  BC Innovations  |  Distillery Techniques

Patient cell-derived, 3-D model of PDAC and tumor microenvironment

TECHNIQUES CATEGORY: Disease models TECHNOLOGY: 3-D models A patient cell-derived 3-D model of PDAC with active fluid motion could be used to screen therapies for the indication. Generation of the model involves: plating primary human...
18:41 , Apr 12, 2019 |  BC Week In Review  |  Company News

Helomics and Viome to study gut microbiome link to ovarian cancer

Helomics partnered with artificial intelligence company Viome to study the link between the gut microbiome and ovarian cancer to develop approaches to help doctors personalize treatment. The collaboration will utilize Helomics’ drug response and genomic...
19:07 , Mar 25, 2019 |  BC Extra  |  Preclinical News

Nanosens debuts latest CRISPR diagnostic on a graphene chip

Nanosens unveiled a device on Monday that can detect genomic mutations in minutes using graphene-based electrical signals instead of chemical labels, making it at least the third company to harness CRISPR as a diagnostic tool...
21:15 , Mar 5, 2019 |  BC Innovations  |  Distillery Techniques

Vascularized kidney organoids for modeling renal disease

TECHNIQUES CATEGORY: Disease models TECHNOLOGY: 3-D models Vascularized kidney organoids could be used to study kidney development and model renal diseases. The organoids are generated in three steps: culturing human pluripotent stem cells with fibroblast...
21:44 , Feb 12, 2019 |  BC Extra  |  Company News

Management tracks: Sanofi, Alexion, bluebird

Sanofi (Euronext:SAN; NASDAQ:SNY) said Ameet Nathwani will become the pharma's first chief digital officer in addition to his current role of EVP, CMO. Alexion Pharmaceuticals Inc. (NASDAQ:ALXN) said SVP, Business Development and Corporate Strategy Aradhana...