07:00 , Jul 28, 2016 |  BC Innovations  |  Distillery Therapeutics

Therapeutics: Spermidine/spermine N1-acetyltransferase 1 (SAT1; SSAT); ornithine decarboxylase (ODC)

Infectious disease INDICATION: Chikungunya virus; viral infection Studies in mammalian cell culture, fruit flies and zebrafish suggest promoting SAT1 expression or inhibiting ODC could help treat Chikungunya, Sindbis and Zika viral infections. In a hamster kidney...
07:00 , Oct 23, 2014 |  BC Innovations  |  Distillery Therapeutics

Indication: Cancer

Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Brain cancer Spermidine/spermine-N1-acetyltransferase 1 (SAT1; SSAT) Studies in patients, mice and cell culture suggest inhibiting SAT1 could...
07:00 , Sep 23, 2010 |  BC Innovations  |  Distillery Therapeutics

Indication: Neurology

Indication Target/marker/pathway Summary Licensing status Publication and contact information Neurology Parkinson's disease (PD) Spermidine/spermine N1-acetyltransferase 1 (SAT1; SSAT) A study in humans and in mice suggests that...
07:00 , May 28, 2009 |  BC Innovations  |  Targets & Mechanisms

New angiogenesis targets

An international collaboration among researchers at the Karolinska Institute, Discovery Genomics Inc. and AngioGenetics AB has produced a set of previously unknown and potentially druggable targets in angiogenesis along with several matching antiangiogenic compounds.1 AngioGenetics was...