18:04 , Aug 29, 2017 |  BC Innovations  |  Distillery Therapeutics

Cancer

INDICATION: Brain cancer Patient sample, cell culture and mouse studies suggest inhibiting S100A4 or depleting S100A4-expressing cells could help treat glioblastoma multiforme (GBM) and other gliomas. In samples from glioma patients, high tumor levels of...
07:00 , May 29, 2014 |  BC Innovations  |  Targets & Mechanisms

S100A9-clot not, bleed not

Although the new generation of antithrombotic drugs provides marked improvements over warfarin, they all still carry bleeding risk. S100 calcium binding protein A9 could represent a new target that, when blocked, prevents thrombosis without increasing...
08:00 , Jan 30, 2014 |  BC Innovations  |  Distillery Therapeutics

Indication: Various

This week in therapeutics Indication Target/marker/pathway Summary Licensing status Publication and contact information Various Allergy; allergic rhinitis; atopic dermatitis S100 calcium binding protein A4 (S100A4) Human and mouse studies suggest inhibiting S100A4 could help treat...