17:09 , Feb 6, 2018 |  BC Innovations  |  Distillery Therapeutics

Cancer

INDICATION: Colorectal cancer Patient sample, cell culture and mouse studies suggest inhibiting HHAT could help treat colorectal cancer. In colorectal cancer cells from patients, siRNA targeting HHAT decreased spheroid formation and size compared with non-specific...
08:00 , Mar 7, 2013 |  BC Innovations  |  Distillery Therapeutics

Indication: Cancer

This week in therapeutics Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Cancer Hedgehog acyltransferase (HHAT); sonic hedgehog homolog (SHH); smoothened (SMO) In vitro studies identified HHAT inhibitors that could help treat SHH-driven...