15:52 , Feb 8, 2017 |  BC Innovations  |  Distillery Therapeutics

Musculoskeletal

INDICATION: Osteoporosis; bone repair Cell culture and mouse studies suggest GNA13 could help treat osteoporosis and bone loss associated with inflammatory osteolysis and rheumatoid arthritis. In a mouse osteoclast cell-based assay of bone resorption, an...
08:00 , Nov 21, 2013 |  BC Innovations  |  Distillery Therapeutics

Indication: Cardiovascular disease

This week in therapeutics Indication Target/marker/pathway Summary Licensing status Publication and contact information Cardiovascular disease Thrombosis Integrin b3 (GPIIIa; CD61); G protein alpha 13 (GNA13) Mouse studies suggest selectively inhibiting CD61 interactions with GNA13 could...
08:00 , Nov 21, 2013 |  BC Innovations  |  Targets & Mechanisms

Riding the integrin wave in thrombosis

The use of platelet integrin a 2b b 3 inhibitors in thrombosis, while clinically very effective, is associated with a high risk of bleeding that has limited their use. Now, researchers at the University of...
08:00 , Feb 5, 2009 |  BC Innovations  |  Distillery Therapeutics

Indication: Inflammation

This week in therapeutics Indication Target/ marker/ pathway Summary Licensing status Publication and contact information Inflammation Anaphylaxis Guanine nucleotide-binding protein (G protein) a11 (Gq class) (GNA11); G protein q polypeptide (GNAQ; Gaq) Studies in mice...