19:20 , Sep 19, 2017 |  BC Innovations  |  Distillery Therapeutics

Neurology

INDICATION: Schizophrenia Mouse studies suggest inhibiting GABRA1 could help treat schizophrenia. In a mouse model of schizophrenia, injection into the nucleus accumbens (NAC) core of an adeno-associated viral (AAV) vector encoding shRNA targeting GABRA1 decreased...
07:00 , Oct 3, 2013 |  BC Innovations  |  Distillery Therapeutics

Indication: Neurology

Indication Target/marker/pathway Summary Licensing status Publication and contact information Neurology Epilepsy NMDA receptor NR1 subtype (GRIN1; NR1); GRIN2B (NR2B); GABAA receptor a1 (GABRA1); GABAA receptor b3 (GABRB3) Human genome sequencing studies suggest modulating GABAA receptors...
08:00 , Jan 8, 2009 |  BC Innovations  |  Cover Story

Taking the inflammation out of epilepsy

Italian and U.S. researchers have proposed treating epileptic seizures by targeting an inflammatory pathway outside the blood-brain barrier: leukocyte migration and recruitment. 1 The strategy potentially could help patients whose seizures are not adequately controlled...