07:00 , Jun 27, 2007 |  BC Extra  |  Clinical News

Nuclease mutations predispose mice to inflammation, cancer

Researchers from the City of Hope National Medical Center, Beckman Research Institute and colleagues reported in Nature Medicine that elimination of two of the three nuclease activities of flap endonuclease 1 ( FEN1 ) in...
07:00 , Jul 22, 2002 |  BC Week In Review  |  Company News

Memory Pharmaceuticals other research news

Researchers published in the Proceedings of the National Academy of Sciences evidence that Fen1 is involved in tumorigenesis. Homozygous deletion of Fen1 in mice resulted in embryonic lethality, however Fen1 heterozygous deleted mice showed a...