21:10 , Jun 21, 2018 |  BC Innovations  |  Translation in Brief

Liver’s killer instinct

A study in Science suggests natural killer T cells residing in the liver uniquely position the organ to reap antitumor effects from antibiotic-mediated microbiome depletion, uncovering a novel link in the microbiome-cancer relationship that highlights...
07:00 , Apr 5, 2012 |  BC Innovations  |  Distillery Therapeutics

Indication: Autoimmune disease

Indication Target/marker/pathway Summary Licensing status Publication and contact information Autoimmune disease Inflammatory bowel disease (IBD); colitis CXC chemokine receptor 6 (CXCR6); chemokine CXC motif ligand 16 (CXCL16) Studies in mice suggest antagonizing CXCR6 or its...
07:00 , Apr 5, 2012 |  BC Innovations  |  Targets & Mechanisms

Bacterial gut shot

Enteric bacteria have long been suspected of helping maintain health, but the specific roles of these microbes have been hard to elucidate. Now, two independent American teams have linked the absence of normal gut bacteria...
07:00 , Mar 15, 2012 |  BC Innovations  |  Distillery Therapeutics

Indication: Neurology

Indication Target/marker/pathway Summary Licensing status Publication and contact information Neurology Neurology CXC chemokine receptor 6 (CXCR6); chemokine CXC motif ligand 16 (CXCL16) Cell culture studies suggest agonizing CXCR6 could help prevent neuronal cell death. In...
07:00 , Oct 9, 2000 |  BC Week In Review  |  Company News

Compugen other research news

CGEN researchers and colleagues published in Nature Immunology the identification of CXCL16, a chemokine expressed by dendritic cells that binds to the Bonzo (STRL33 or TYMSTR) receptor on T cells, which is a co-receptor for...