22:22 , Mar 18, 2019 |  BC Extra  |  Company News

Astellas adds more drug delivery tech via NapaJen deal

Astellas has completed a second deal for a drug delivery technology, this time with NapaJen, that stands to add a new modality to its pipeline. Astellas Pharma Inc. (Tokyo:4503) will use oligonucleotide delivery technology from...
03:38 , Jan 11, 2019 |  BC Innovations  |  Product R&D

PureTech turns inward

After a 15-year run of spinning out technologies into affiliate companies, PureTech Health plc is stepping away from that model in favor of an internal pipeline to advance its new platforms. Behind the structural shift...
07:00 , Jun 18, 2015 |  BC Innovations  |  Distillery Techniques

Techniques: Oral, macrophage-targeted nanoparticles to deliver inflammatory disease therapies

Drug delivery TECHNOLOGY: Nanoparticles Macrophage-targeted nanoparticles could help deliver anti-inflammatory therapeutics. The nanoparticles were synthesized by colloidal formation of chitosan, tripolyphosphate, alginate, and a glucan that binds C-type lectin domain family 7 member A (...
07:00 , Aug 14, 2014 |  BC Innovations  |  Distillery Therapeutics

Indication: Infectious disease

Indication Target/marker/pathway Summary Licensing status Publication and contact information Infectious disease Aspergillus C-type lectin domain family 7 member A (CLEC7A; DECTIN1); laminarin In vitro and mouse studies suggest DECTIN1 chimeric antigen receptor (CAR)-expressing T cells...
08:00 , Nov 19, 2009 |  BC Innovations  |  Distillery Therapeutics

Indication: Infectious disease

Indication Target/marker/pathway Summary Licensing status Publication and contact information Infectious disease Fungal infections C-type lectin domain family 7 member A (CLEC7A; DECTIN1) Genetic studies identified a mutation in DECTIN1 that could help predict susceptibility to...
07:00 , Sep 17, 2009 |  BC Innovations  |  Distillery Therapeutics

Indication: Infectious Disease

Indication Target/marker/ pathway Summary Licensing status Publication and contact information Infectious disease Candida C-type lectin domain family 7, member A (CLEC7; DECTIN1); C-type lectin domain family 6, member A (CLEC6; DECTIN2) Studies in cell culture...