18:40 , Aug 8, 2018 |  BC Innovations  |  Emerging Company Profile

Catching antibodies with polymers

Polyneuron Pharmaceuticals AG's glycopolymers act as decoys for the autoantibodies that drive autoimmune diseases, such as anti-MAG neuropathy, and are designed to be more effective and safer than other therapies. Polyneuron's Antibody-Catch platform generates glycopolymers...
07:00 , Jun 9, 2016 |  BC Innovations  |  Distillery Therapeutics

Therapeutics: Lipopolysaccharide (LPS)

Hematology INDICATION: Transfusion Mouse studies suggest pre-activating a subset of dendritic cells (DCs) could prevent alloimmunity to non- ABO antigens in transfusion patients. In mice transfused with red blood cells (RBCs), depletion of the cDC2...
08:00 , Feb 10, 2014 |  BioCentury  |  Emerging Company Profile

Amyndas: Complement shutdown

Transatlantic sister companies Amyndas Pharmaceuticals S.A. and Amyndas Pharmaceuticals LLC are developing therapies to treat complement-mediated disorders that could be more potent than other complement inhibitors, potentially opening up new indications. Lead candidate Amanden comes...
07:00 , May 10, 2012 |  BC Innovations  |  Distillery Techniques

Technology: Assays & screens

Approach Summary Licensing status Publication and contact information Assays & screens Paper-based assay for reporting blood type as text A paper-based assay was used to identify and display blood type as text. The paper assays...
08:00 , Feb 10, 2011 |  BC Innovations  |  Distillery Therapeutics

Indication: Cardiovascular disease

Indication Target/marker/pathway Summary Licensing status Publication and contact information Cardiovascular disease Coronary artery disease (CAD); myocardial infarction (MI) ABO blood group (ABO); ADAM metallopeptidase with thrombospondin type 1 motif 7 (ADAMTS7) Genomewide association studies identified...
08:00 , Mar 4, 2010 |  BC Innovations  |  Distillery Therapeutics

Indication: Infectious disease

Indication Target/marker/pathway Summary Licensing status Publication and contact information Infectious disease Bacterial infection ABO blood group (ABO) In vitro and mouse studies suggest that the lectins galectin-4 (LGALS4; GAL-4) and LGALS8 (GAL-8) could help kill...
07:00 , Aug 20, 2009 |  BC Innovations  |  Distillery Therapeutics

Indication: Cancer

Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Pancreatic cancer ABO blood group (ABO); sonic hedgehog homolog (SHH) A genomewide association study identified SNPs associated with ABO and SHH that could help predict...
07:00 , Apr 9, 2007 |  BioCentury  |  Tools & Techniques

O, what a simple solution

Blood substitutes have been a black hole for biotech companies. There are no such products approved by FDA or EMEA after nearly two decades of effort. Nevertheless, candidates that attempt to replace the oxygen-carrying ability...