07:00 , Aug 4, 2016 |  BC Innovations  |  Distillery Therapeutics

Therapeutics: AP2 associated kinase 1 (AAK1)

Neurology INDICATION: Pain Mouse and rat studies suggest inhibiting AAK1 could help treat neuropathic pain. In a mouse model of chemical-induced or spinal nerve ligation-induced neuropathic pain, AAK1 knockout decreased measures of pain compared with...
07:00 , Oct 30, 2008 |  BC Innovations  |  Tools & Techniques

Expanding the kinase kingdom

Researchers at Harvard Medical School , the Dana-Farber Cancer Institute and Brigham and Women's Hospital have applied loss-of-function small hairpin RNA screens to various human cell lines to identify kinases that are essential for cell...