BC Innovations | Sep 27, 2017
Distillery Techniques

Chemistry

TECHNOLOGY: Synthetic chemistry A scalable, cobalt nanoparticle-based method for incorporating amine functional groups into drug-like molecules could facilitate drug production and the exploration of chemical space. The nanoparticles consist of a cobalt core encapsulated in...
BC Week In Review | Jul 2, 2012
Clinical News

Vastarel MR regulatory update

EMA's CHMP recommended removing indications for treatment of vertigo, tinnitus and vision disturbance for trimetazidine-containing products and restricting their use as an add-on therapy for stable angina pectoris in patients who failed, or are intolerant...
BC Innovations | Aug 26, 2010
Distillery Therapeutics

Indication: Cardiovascular disease

Indication Target/marker/pathway Summary Licensing status Publication and contact information Cardiovascular disease Hypertension Malonyl-CoA decarboxylase (MLYCD; MCD); pyruvate dehydrogenase kinase (PDK); 3-ketoacyl-CoA thiolase (ACAA2) A study in mice suggests that inhibiting MCD, PDK or ACAA2 could...
BC Innovations | Aug 26, 2010
Targets & Mechanisms

Metabolic origins for pulmonary hypertension

Researchers at the University of Alberta and Metabolic Modulators Research Ltd. have shown that a pathological shift toward glycolysis could be responsible for the deleterious vascular remodeling seen in pulmonary arterial hypertension. 1 The findings...
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