...a fatty acid transporter, could treat HER2-positive breast cancer and sensitize tumors resistant to Tykerblapatinib... ...cells and a CD36 inhibitor tool compound sensitized the cells to Tyverb. In mice with Tykerb-resistant... ...Kurokawa, Dartmouth College, Hanover, N.H.; Kent State University, Kent, Ohio email: mkurokaw@kent.edu
Claire Quang
Tykerb, Tyverb, lapatinib (GW572016)
Dartmouth...
...data for Kadcyla. In EMILIA, Kadcyla posted an ORR of 43.6% vs. 30.8% for Tykerblapatinib... ...lapatinib plus capecitabine and a median PFS of 9.6 months vs. 6.4 months for the Tykerb...
...models. In additional PDX models, the DHODH inhibitor Aubagio teriflunomide in combination with either Tykerblapatinib... ...leukemia (AML) and Phase I testing for solid tumors. Novartis AG and Eddingpharm Inc. market Tykerb... ...of California San Diego, La Jolla, Calif. email: drjeremyrich@gmail.com
Claire Quang
Aubagio, teriflunomide (HMR1726)
buparlisib (BKM120)
Tykerb, Tyverb, lapatinib (GW572016)
University...