BioCentury | Oct 31, 2018
Distillery Therapeutics

Ophthalmic disease

...human LIF fused to bacterial dihydrofolate reductase (DHFR), which is stabilized by the antibiotic Primsol trimethoprim...
...testing the fusion protein in additional animal models of blindness. Allegis Pharmaceuticals LLC markets Primsol trimethoprim...
...John. D Ash, University of Florida, Gainesville, Fla. email: jash@ufl.edu Jaime De Leon Primsol (Brand), trimethoprim (Generic), Primsol...
BioCentury | Sep 13, 2018
Company News

Gottlieb rebukes Nostrum's 300% price hike for generic antibiotic

...WAC of $2,392.32 for a 240 mL package. The Infectious Disease Society of America recommends trimethoprim-sulfamethoxazole...
BioCentury | Sep 11, 2018
Company News

Gottlieb rebukes Nostrum’s 300% price hike for generic antibiotic

...WAC of $2,392.32 for a 240 mL package. The Infectious Disease Society of America recommends trimethoprim-sulfamethoxazole...
BioCentury | Mar 14, 2018
Translation in Brief

MOA the same

...that four of the GSK compounds predicted to have a mode of action similar to trimethoprim...
...predicts mode of action of uncharacterized antimicrobial compounds.” Science Translational Medicine (2018) Jaime de León, Staff Writer trimethoprim ETH...
BioCentury | Aug 9, 2017
Distillery Techniques

Imaging

...TECHNOLOGY: PET A trimethoprim-based PET imaging agent could help distinguish bacterial infections from cancer or inflammation...
...PET agent consisted of a fluorine-18 [ 18 F] radionuclide-labeled analog of the generic antibiotic trimethoprim...
...agent in mouse models of S. aureus infection combined with cancer or inflammation. DESCRIPTION: A trimethoprim-based...
BioCentury | Apr 11, 2016
Company News

Aytu, Allegis deal

...Aytu granted Allegis exclusive rights to co-promote Primsol trimethoprim in the U.S. Allegis will promote the...
...the drug to pediatricians; Aytu retains all other rights. Primsol, a liquid formulation of antibiotic trimethoprim...
BioCentury | Jan 25, 2016
Company News

Promiliad, Spero Therapeutics, University of Connecticut deal

...Spero said the DHFR program expands the antibacterial spectrum of an undisclosed antifolate to treat trimethoprim-resistant...
BioCentury | Aug 7, 2014
Clinical News

Continuous treatment reduces malaria risk in young children

...episodes per person year in the DP group compared to 5.21 for children receiving daily trimethoprim/sulfamethoxozole...
BioCentury | Aug 20, 2012
Clinical News

Bactramin regulatory update

...Ministry of Health Labor and Welfare approved an application to expand the label for Bactramin sulfamethoxazole/trimethoprim...
...Co. Ltd. (Tokyo:4519), Tokyo, Japan Roche (SIX:ROG; OTCQX:RHHBY), Basel, Switzerland Product: Bactramin ( Bactrim ) sulfamexothazole/trimethoprim...
BioCentury | Feb 20, 2012
Clinical News

Bactramin regulatory update

...Chugai submitted a regulatory application in Japan to expand the label of antibiotic Bactramin sulfamethoxazole/trimethoprim to...
...Co. Ltd. (Tokyo:4519), Tokyo, Japan Roche (SIX:ROG; OTCQX:RHHBY), Basel, Switzerland Product: Bactramin ( Bactrim ) sulfamexothazole/trimethoprim...
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