...patients ages 13-34 with congenital or childhood-onset myotonic dystrophy type 1 (DM1) showing that tideglusib (AMO-02... ...of once-daily 400 or 1,000 mg oral tideglusib. The company said most patients treated with tideglusib... ...type 1 (DM1) Endpoint: Safety Status: Phase II data Milestone: NA
Jennie Walters
tideglusib (AMO-02, np-12, Nypta, Zentylor)
AMO...
...mouse models of GBM, the GSK3β inhibitor tideglusib decreased tumor growth and increased survival, and tideglusib... ...animal models of other brain cancers. Noscira S.A. and AMO Pharma Ltd. have tideglusib ( AMO-02...
...AMO-01's primary competitors. The synthetic analog of glycine-proline-glutamate is in Phase II. AMO's second program, AMO-02... ...DM1, Steinert's disease). AMO-02, an inhibitor of glycogen synthase kinase 3 beta (GSK3B) formerly dubbed tideglusib... ...hyperphosphorylation of tau. Data reported in The Journal of Clinical Investigation in 2012 showed an AMO-02...