...whether to implement a REMS program for Thalomid...

...degraders that make broader use of the “degron” structures grabbed by the field’s first drugs, thalidomide...

...degraders that make broader use of the “degron” structures grabbed by the field’s first drugs, thalidomide...
...role. The company is going after targets containing degrons -- the glycine loop structures that thalidomide...

...targeting chimeras because they are easier to rationally design. In contrast, molecular glue therapies like thalidomide...

...CASTOR and the OPTIMISMM Phase III studies” of anti-CD38 mAb Darzalex daratumumab plus Vd and thalidomide...
...A/S Genmab A/S (CSE:GMAB; NASDAQ:GMAB) and Johnson & Johnson (NYSE:JNJ) is approved in combination with thalidomide...

...anti-CD-38 mAb from the Janssen-Cilag International NV unit of Johnson & Johnson (NYSE:JNJ), with bortezomib, thalidomide...

...new thalidomide-dependent CRBN substrates that could be applied to screens for new, safer thalidomide derivatives. Thalidomide...
...Thalidomide was banned in the 1960s before gaining approval for multiple myeloma in 1998 as Thalomid...
...4 TP63 (p63) - Tumor protein p63 Inhua Muijrers-Chen, Associate Editor Thalomid, thalidomide (Actimid, CDC 394, Synovir, Thalidomide Celgene, Thalidomide Pharmion) Avadomide...

...Neotribe Ventures. Companies have been interested in developing E3 ligase modulators since the discovery that thalidomide...

...in China" ). Hongjiang Li, Staff Writer Kymriah, tisagenlecleucel (CTL019, cart-19, tisagenlecleucel-t) Thalomid, thalidomide (Actimid, CDC 394, Synovir, Thalidomide Celgene, Thalidomide Pharmion) Cellular...

...Review from FDA for an sBLA for Darzalex daratumumab in combination with Velcade bortezomib, Thalomid thalidomide...