BioCentury | Oct 31, 2018
Distillery Therapeutics

Hepatic; renal

...a human kidney epithelial cell line treated with the generic chemotherapy cisplatin, the ACMSD inhibitor TES-1025...
...and plasma markers of liver damage. In a mouse model of cisplatin-induced AKI, pretreatment with TES-1025...
...testing of TES-1025 and TES-991 in NAFLD and AKI patients. TES Pharma has TES-991 and TES-1025...
BioCentury | Oct 25, 2018
Preclinical News

Inhibiting metabolic enzyme to prevent NAFLD, acute kidney injury

...study , the team aimed to target the NAD+ synthesis pathway by developing TES-991 and TES-1025...
...inflammation and plasma biomarkers of liver damage in a mouse model of diet-induced NAFLD. Prophylactic TES-1025...
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