BioCentury | Dec 2, 2020
Emerging Company Profile

Sofinnova’s Papiernik, Costa and Roche alum Garibaldi carve orphan neurology play Noema out of the pharma’s assets

...treat trigeminal neuralgia is the anticonvulsant Tegretol carbamazepine...
...receptor subtype 5 (mGluR5) (GRM5)Phosphodiesterase-10A (PDE-10A) Danielle Golovin Tegretol, carbamazepine Sofinnova...
BioCentury | Oct 17, 2016
Clinical News

IV carnexiv carbamazepine regulatory update

...an NDA from H. Lundbeck for IV Carnexiv carbamazepine as short-term replacement therapy for oral carbamazepine...
...Pharmaceuticals Inc. (NASDAQ:LGND), La Jolla, Calif. H. Lundbeck A/S (CSE:LUN), Copenhagen, Denmark Product: IV carnexiv carbamazepine...
BioCentury | Sep 26, 2016
Clinical News

Zebinix: Phase III data

...III trial showed that once-daily oral Zebinix met the primary endpoint of non-inferiority to twice-daily carbamazepine...
...seizure freedom (71.1% vs. 75.6%). The non-inferiority margin was 12%. Zebinix was also non-inferior to carbamazepine...
BioCentury | May 2, 2016
Clinical News

IV Carnexiv carbamazepine regulatory update

...for IV Carnexiv carbamazepine to treat epilepsy in patients who temporarily cannot take their oral carbamazepine...
...Pharmaceuticals Inc. (NASDAQ:LGND), La Jolla, Calif. H. Lundbeck A/S (CSE:LUN), Copenhagen, Denmark Product: IV Carnexiv carbamazepine...
BioCentury | Oct 19, 2015
Clinical News

Vimpat lacosamide: Phase III data

...adult patients with partial-onset seizures showed that lacosamide met the primary endpoint of non-inferiority to carbamazepine-CR...
BioCentury | Oct 19, 2015
Clinical News

Vimpat lacosamide: Phase III data

...adult patients with partial-onset seizures showed that lacosamide met the primary endpoint of non-inferiority to carbamazepine-CR...
BioCentury | Apr 30, 2015
Distillery Techniques

Therapeutics: Theiler's murine encephalomyelitis virus (TMEV)-infected mouse model of infection-induced epilepsy

...seizures, decreased anxiety and increased motor performance compared with vehicle, whereas the generic anti-seizure drug carbamazepine...
BioCentury | Jun 23, 2014
Product Development

Nav(1.7)igating pain

...ideation. Traditional analgesics such as opioids don't effectively treat trigeminal neuralgia. Epilepsy drugs such as carbamazepine...
...role in the condition. The trial enrolled trigeminal neuralgia patients who were being treated with carbamazepine...
...CNV1014802 three times a day in a three-week open-label period as they were titrated off carbamazepine...
BioCentury | Mar 17, 2014
Clinical News

IV Carbella carbamazepine regulatory update

...carbamazepine as replacement therapy in adults who are on a stable maintenance oral dose of carbamazepine...
...who cannot take anything by mouth. H. Lundbeck A/S (CSE:LUN), Copenhagen, Denmark Product: IV Carbella carbamazepine...
BioCentury | Aug 19, 2013
Clinical News

IV carbamazepine regulatory update

...disclosed in its 2Q13 earnings that in June FDA granted Orphan Drug designation for IV carbamazepine...
...mouth. The sodium channel blocker is in Phase III testing for short-term replacement of oral carbamazepine...
...submission to FDA slated towards year end. H. Lundbeck A/S (CSE:LUN), Copenhagen, Denmark Product: IV carbamazepine...
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