...low NFE2L2 transcript levels were associated with larger β amyloid plaques. In mice with AD, sulforaphane...

...INDICATION: Dermatology Mouse and cell culture studies suggest RHBDF2 inhibition or sulforaphane could help treat palmoplantar...
...sulforaphane (SFX-01, Sulforadex), a complex of sulforaphane and α-cyclodextrin in a stable powder developed using Sulforadex...
...London, U.K. email: d.p.kelsell@qmul.ac.uk CONTACT: Anissa Chikh, same affiliation as above email: a.chikh@qmul.ac.uk Chris Lieu sulforaphane (SFX-01, Sulforadex) Queen...

...Evgen began the open-label, European Phase II STEM trial to evaluate 300 mg oral SFX-01 twice...
...Molecular target: NA Description: Complex of sulforaphane and alpha-cyclodextrin in a stable powder developed using Sulforadex...
...PFS), overall survival (OS) and time to next treatment Status: Phase II started Milestone: NA Julian Zhu SFX-01 sulforaphane Evgen...

...An independent DSMB recommended continuation of the double-blind, placebo-controlled, U.K. Phase II SAS trial of SFX-01...
...a nasogastric tube based on an interim safety review. The trial is evaluating 300 mg SFX-01...
...Molecular target: NA Description: Complex of sulforaphane and alpha-cyclodextrin in a stable powder developed using Sulforadex...

...Dermatology INDICATION: Dermatology Patient sample and mouse studies suggest the NFE2L2 activator sulforaphane could help treat...
...skin samples from healthy volunteers. In a mouse model of pachyonychia congenita, topical application of sulforaphane...
...include testing sulforaphane in other models of pachyonychia congenita. Evgen Pharma plc has sulforaphane ( SFX-01...

...oral SFX-01 twice daily for up to 28 days plus nimodipine in about 90 patients. SFX-01...
...Molecular target: NA Description: Complex of sulforaphane and alpha-cyclodextrin in a stable powder developed using Sulforadex...

...Evgen exercised a 2013 option to acquire exclusive, worldwide rights to 60 sulforaphane analogs from the...
...plus royalties that will not exceed 1%. Evgen’s SFX-01 , a synthetic, stabilized form of sulforaphane...

...I/II testing of SFX-01 in prostate and breast cancers and Phase II testing of the sulforaphane...

...to elevated superoxide levels to be impeded specifically in fibrotic cells of aged mice. Accordingly, sulforaphane...

...did no injury. In the same models, Nox2 knockout or treatment with the generic antioxidant sulforaphane...