BioCentury | Apr 1, 2020
Distillery Therapeutics
FLNA identified as a target for epilepsy associated with focal cortical dysplasia type II
...II, an shRNA against FLNA lowered seizure frequency by 83% and prevented disease-associated neuronal misplacement, soma...
...model, the small molecule FLNA inhibitor PTI-125 given before or after seizure onset lowered neuronal soma...
...model, the small molecule FLNA inhibitor PTI-125 given before or after seizure onset lowered neuronal soma...