...and Middle-East respiratory syndrome (MERS) coronaviruses. The 17 drugs -- including chloroquine, hydroxychloroquine, cancer therapy tamoxifen...

...growth of two human tamoxifen-resistant breast cancer cell lines. In a xenograft mouse model of tamoxifen-resistant...

...poor response to tamoxifen in breast cancer patients, and inhibiting the enzyme increased sensitivity to tamoxifen...

...non-specific siRNA, and in the tamoxifen-resistant breast cancer cell line, the two ANKLE2-targeting siRNAs plus tamoxifen...
...breast cancer cell line, the two ANKLE2-targeting siRNAs plus tamoxifen increased cell death compared with tamoxifen...
...of tamoxifen-resistant breast cancer, tumor-specific knockdown of ANKLE2 plus tamoxifen decreased tumor size compared with tamoxifen...

...p≤0.05). In 24 ovarian cancer and 49 stomach adenocarcinoma patients, the model predicted resistance to tamoxifen...

...for eight days with either the TM7SF2 inhibitor ifenprodil (n=6; p=0.0004) or the EBP inhibitor tamoxifen...
...measurements confirmed the treated animals had higher levels of sterols in their brains (ifenprodil, p=0.0003; tamoxifen...
...remyelination, supporting the claim that remyelination depends more on 8,9-unsaturated sterol production than muscarinic inhibition. Tamoxifen...

...oral administration of the compound decreased tumor growth compared with subcutaneous Faslodex fulvestrant or oral tamoxifen...
...Faslodex, a selective estrogen receptor down-regulator (SERD), for breast cancer. The generic estrogen receptor antagonist tamoxifen...

...will acquire Pear Tree Pharmaceuticals Inc. (Cambridge, Mass.), gaining its PT-101. The vaginal formulation of tamoxifen...

...sample and cell culture studies suggest inhibiting BARD1, BRCA1, CDK1 or CKD12 could help treat tamoxifen-resistant...
...cancer. In tumor tissue from 27 recurrent breast cancer patients whose tumors became resistant to tamoxifen...
...and BRCA1 expression was higher in relapsed tumors than in matched primary tumors. In two tamoxifen-resistant...

...normal expression. In the genetic model, knockout of PDGFCC plus the generic estrogen receptor antagonist tamoxifen...
...PDGFCC knockout alone. In two orthotopic mouse models of breast cancer, an anti-PDGFCC mAb plus tamoxifen...
...published online March 12, 2018 doi:10.1038/nm.4494 CONTACT: Kristian Pietras, Lund University, Lund, Sweden email: kristian.pietras@med.lu.se Chris Lieu tamoxifen Lund...