...dose-escalation, U.S. Phase Ib/IIa trial showed that the maximum tolerated dose (MTD) of twice-weekly IV SNS01-T... ...events reported were fatigue, infusion reaction, nausea, thrombocytopenia and chills, with no treatment-related deaths. Additionally, SNS01-T... ...SNS01-T Business: Cancer Molecular target: Eukaryotic translation initiation factor 5A (eIF5A) Description: Modified formulation of SNS01...
...an open-label, dose-escalation, U.S. Phase Ib/IIa trial evaluating 0.0125, 0.05, 0.2 and 0.375 mg/kg IV SNS01-T... ...company said there were 2 dose-limiting toxicities (DLT) in the 8-patient cohort receiving 0.375 mg/kg SNS01-T... ...SNS01-T Business: Cancer Molecular target: Eukaryotic translation initiation factor 5A (eIF5A) Description: Modified formulation of SNS01...
...developing Senesco's SNS01-T and bringing undisclosed candidates to the clinic in the next two years. SNS01-T... ...chronic lymphocytic leukemia (CLL) and non-Hodgkin's lymphoma (NHL). The product is a modified formulation of SNS01...
...cohort of an open-label, dose-escalation, U.S. Phase Ib/IIa trial showed that twice-weekly 0.2 mg IV SNS01-T... ...blood and a second patient with DLBCL had evidence of tumor shrinkage in some lesions. SNS01-T... ...SNS01-T Business: Cancer Molecular target: Eukaryotic translation initiation factor 5A (eIF5A) Description: Modified formulation of SNS01...
...continuation to the fourth cohort of an open-label, dose-escalation, U.S. Phase Ib/IIa trial of IV SNS01-T... ...and evaluate 0.375 mg/kg SNS01-T. The trial is evaluating 0.0125, 0.05, 0.2 and 0.375 mg/kg SNS01-T... ...SNS01-T Business: Cancer Molecular target: Eukaryotic translation initiation factor 5A (eIF5A) Description: Modified formulation of SNS01...
...the second cohort of an open-label, dose-escalation, U.S. Phase Ib/IIa trial showed that 0.05 mg/kg SNS01-T... ...to 1 case of stable disease in a MM patient at weeks 3 and 6. SNS01-T... ...SNS01-T Business: Cancer Molecular target: Eukaryotic translation initiation factor 5A (eIF5A) Description: Modified formulation of SNS01...
...Senesco said it amended an open-label, dose-escalation, U.S. Phase Ib/IIa trial of twice-weekly IV SNS01-T for... ...MCL. The trial is evaluating 0.0125, 0.05, 0.2 and 0.375 mg/kg SNS01-T in 15 patients. SNS01-T... ...SNS01-T Business: Cancer Molecular target: Eukaryotic translation initiation factor 5A (eIF5A) Description: Modified formulation of SNS01...
...the first cohort of an open-label, dose-escalation, U.S. Phase Ib/IIa trial showed that 0.0125 mg/kg SNS01-T... ...SNS01-T twice weekly for 6 weeks in about 15 patients with relapsed or refractory MM. SNS01-T... ...SNS01-T Business: Cancer Molecular target: Eukaryotic translation initiation factor 5A (eIF5A) Description: Modified formulation of SNS01...