BioCentury | Jun 11, 2020

In course correction, AbbVie steers toward innovation with Genmab deal

AbbVie’s Genmab deal gives it a ticket to one of the hottest modality spaces, albeit as a latecomer. The pharma gains bispecific antibodies to add to its ADCs and standard mAbs, extending its tool kit...
BioCentury | May 25, 2020

New additions to the IPO queue: Generation Bio, Avidity, Vaxcyte and more

Now that investors have demonstrated demand for biotech IPOs that has led to a warm reception for new listings over the past few weeks, the queue has begun to grow again, as a handful of...
BioCentury | Apr 27, 2020

ADC renews IPO bid as first regulatory filing looms

Less than four months after new pivotal data strengthened its case for a BLA submission this year, ADC has again filed a prospectus for an IPO -- although it may be a more modest one...
BioCentury | Apr 14, 2020

COVID-19 pushes J&J to slash guidance; vaccine initiative on track

Johnson & Johnson cut its guidance Tuesday as it braced for its bottom line to take a hit from the pandemic. The update came as the company topped consensus estimates for the first quarter and...
BioCentury | Apr 14, 2020

Blackstone makes largest-ever life sciences investment in Alnylam

Blackstone’s $2 billion investment in Alnylam is a departure from its other life sciences investments in size and scope, but the deal still fits the investor’s core model of focusing on products rather than companies....
BioCentury | Mar 20, 2020

Strong investor demand for InnoCare on HK exchange despite pandemic concerns

Despite ongoing turbulence in the global financial markets, strong demand by local investors enabled InnoCare to price its IPO on the Hong Kong exchange's biotech chapter at the top of its proposed range, valuing the...
BioCentury | Mar 7, 2020
Emerging Company Profile

Kira: depleting activated dendritic cells

First-in-class mAbs against activated dendritic cells from Australian newco Kira could block the inflammation and immune response associated with GvHD and autoimmune diseases without the risk of infection that accompanies broad immunosuppression. Founding CEO Dan...
BC Extra | Jan 9, 2020
Clinical News

ADC’s loncastuximab data could clear path for BLA, IPO filing

Months after scuttling a planned listing, ADC Therapeutics intends to refile for an IPO as it prepares to submit a BLA in 3Q19 seeking accelerated approval for its antibody-drug conjugate to treat DLBCL in a...
BC Extra | Dec 17, 2019
Clinical News

BeiGene looks beyond Phase III setback to build case for Brukinsa

Although a Phase III miss in Waldenström’s macroglobulinemia scuttles Brukinsa’s near-term chances to add a superiority claim to its label, BeiGene believes the Btk inhibitor's combined efficacy and safety profile differentiates it from Imbruvica. BeiGene...
BC Extra | Dec 13, 2019
Preclinical News

Dec. 12 Preclinical Quick Takes: POC for Aptose blood cancer candidate, plus Penn-Acorn AI, Neurimmune-Biogen and Syndax

Efficacy for Btk, FLT3 inhibitor in blood cancers  In a pair of posters at the American Society of Hematology (ASH) meeting in Orlando, Aptose Biosciences Inc. (NASDAQ:APTO; TSX:APS) and University of Texas MD Anderson Cancer...
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