BioCentury | Feb 22, 2020
Translation in Brief

Storm's open-access algorithm for RNA epigenetics; plus Duke studies show checkpoint blockers promote anti-HIV bNAbs and reduce opioid efficacy

...mice one hour before a morphine injection increased behavioral responses to pain stimuli compared with morphine...
BioCentury | Feb 7, 2020
Translation in Brief

Gilead’s remdesivir vs. 2019-nCov in cells; plus Syndax, Syntrix and Max Planck

...recruitment thought to mediate the opiate-induced respiratory depression caused by other opiates including fentanyl and morphine...
BioCentury | Feb 1, 2020
Company News

Any chance left for safer opioids?

...failure. For example, heroin was introduced by Bayer AG (Xetra:BAYN) as an abuse-deterrent alternative to morphine...
...language on the labels dissuades payers from reimbursing them. For example, the label for Embeda morphine/naltrexone...
...Corp. was founded in 2010 to develop tamper-resistant opioid pain medications and its Arymo ER morphine...
BioCentury | Jan 7, 2020
Financial News

BioIntervene takes on adenosine in pain, raises $30M

...In a model of neuropathic pain, BIO-205 was more efficacious and potent than gabapentin or morphine...
BioCentury | Sep 19, 2019
Distillery Therapeutics

Inhibiting GPR139 for opioid withdrawal

...C. elegans homolog of GPR139 with regulation of morphine sensitivity. In a mouse model of morphine...
BioCentury | Feb 20, 2019
Distillery Therapeutics

Neurology

...with free Leu-enkaphalin neuropeptide or empty nanoparticles and with a longer duration of action than morphine...
BioCentury | Dec 8, 2018
Regulation

Path to opioid-free pain relief

...adjunctive opioid analgesics "Efficacy was demonstrated as a statistically significant greater reduction in the mean morphine...
...of this is reflected in the finding that patients treated with SPRIX required 36% less morphine...
BioCentury | Dec 4, 2018
Distillery Therapeutics

Neurology

...of morphine -- a heroin metabolite -- in the dam and fetus, brain levels of morphine...
BioCentury | Nov 9, 2018
Clinical News

FDA approves AcelRx, Coherus, Pfizer Products, rebuffs Trevena's Olinvo

...Advisory Committee voted 8-7 against recommending approval of Olinvo (see "Trevena Goes for MOR than Morphine"...
BioCentury | Nov 2, 2018
Company News

FDA approves AcelRx, Coherus, Pfizer products, rebuffs Trevena's Olinvo

...Advisory Committee voted 8-7 against recommending approval of Olinvo (see "Trevena Goes for MOR than Morphine"...
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