...By Claire Quang, Staff Writer DISEASE CATEGORY: CancerINDICATION: Breast cancerAn antibody-drug conjugate comprising anti-HER2 antibody trastuzumab...
...inhibited growth with IC50 values 20-200 times lower than marketed ADC Kadcyla ado-trastuzumab emtansine, which conjugates trastuzumab...
...DM1. In a xenograft mouse model of TNBC with 17p loss and low HER2 expression, the trastuzumab-α-amanitin...

...GmbH.Seagen’s Tuksya gains EU approvalThe European Commission approved Tuksya tucatinib from Seagen Inc. (NASDAQ:SGEN) plus trastuzumab...

...cancer drugs, such as Rituxan rituximab and Herceptin trastuzumab...

...Hemlibra emicizumab-kxwh. He was also involved in the launches of Herceptin trastuzumab, Perjeta pertuzumab and Kadcyla ado-trastuzumab...
...non-Hodgkin lymphoma (NHL) therapy.“What excites me and motivates me is novel therapies with transformational potential. Herceptin...

...NK cells conjugated with the anti-HER2 antibody trastuzumab...

...plc (LSE:AZN; NASDAQ:AZN) and Daiichi Sankyo Co. Ltd. (Tokyo:4568) said HER2-targeted antibody-drug conjugate (ADC) Enhertu fam-trastuzumab...
...advanced or metastatic HER2-positive gastric or gastroesophageal junction adenocarcinoma patients who have received a prior trastuzumab-based...

...data showing zanidatamab led to a confirmed objective response rate (ORR) of 47% in 15 Herceptin trastuzumab-naïve...
...HER2 domains as Herceptin and Perjeta pertuzumab from Roche (SIX:ROG; OTCQX:RHHBY).Zymeworks believes zanidatamab will be better than a Herceptin-Perjeta...

...have improved progression-free survival (PFS) versus Herceptin trastuzumab...

...company that you can’t carry and replace Herceptin...

...or high-flow oxygen or other non-invasive ventilation at the start of treatment. The committee also backed Enhertu trastuzumab...
...ligand 1TNF – Tumor necrosis factorTROP2 (TACSTD2; EGP-1) – Tumor-associated calcium signal transducer 2 Sandi Wong Veklury, remdesivir (GS-5734) Enhertu, fam-trastuzumab...