BC Week In Review | Jun 15, 2015
Clinical News

EP-100: Phase II data

The open-label, U.S. Phase II ESP2011-002 trial in 44 evaluable patients with advanced ovarian cancer showed that IV EP-100 plus paclitaxel led to an ORR, the primary endpoint, of 34.8% vs. 33.3% for paclitaxel alone....
BC Week In Review | Jun 11, 2012
Clinical News

EP-100: Phase I data

An open-label, dose-escalation, U.S. Phase I trial in 38 patients with LHRH-positive solid tumors showed that twice-weekly IV EP-100 for 3 weeks of a 4-week cycle was generally well tolerated and led to 5 cases...
BC Week In Review | May 28, 2012
Clinical News

EP-100: Phase II started

Esperance began an open-label, U.S. Phase II trial (ESP2011-002) to compare an IV infusion of EP-100 twice weekly for the first 3 weeks of a 4-week cycle for up to 6 cycles plus weekly IV...
BC Innovations | Apr 21, 2011
Strategy

A conversation with Gregory Verdine

What will drugs look like in the coming decade? This is the question being posed by Gregory Verdine and the next-generation therapeutic modalities team he leads at Third Rock Ventures . One answer, Verdine believes, is...
BC Week In Review | Sep 14, 2009
Clinical News

EP-100: Phase I started

Esperance began an open-label, dose-escalation, U.S. Phase I trial to evaluate intravenous EP-100 given for 3 weeks of a 4-week cycle in up to 36 patients. Esperance Pharmaceuticals Inc. , Baton Rouge, La.   Product: EP-100...
BC Week In Review | Apr 27, 2009
Clinical News

Esperance preclinical data

In a mouse xenograft model of ovarian cancer, weekly injections of EP-100 at doses as low as 0.2 mg/kg led to significant tumor regression from baseline (p<0.03), while tumor growth was observed in mice receiving...
BioCentury | Feb 2, 2009
Emerging Company Profile

Esperance: Harmonizing hormones to cancer

Based on a technology invented at Louisiana State University as a means of sterilizing animals, Esperance Pharmaceuticals Inc. is developing fusion proteins that combine a tumor-seeking hormone receptor ligand and a cytotoxin to treat cancer....
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