BioCentury | Mar 3, 2016
Distillery Therapeutics

Therapeutics: An undetermined target

...and testing in human muscle cell-based assays yielded four compounds that inhibited enterovirus 71 ( EV71...
...fourth inhibited replication of the six viruses with EC50 values of 0.5-340 nM. In an EV71-infected...
BioCentury | Feb 2, 2016
Financial News

Sinovac mulls take-private proposal

...in China. This half, it expects to launch its EV71 vaccine against human enterovirus 71 (EV71...
BioCentury | Jan 25, 2016
Clinical News

EV71 vaccine regulatory update

...company’s EV71 vaccine against hand, foot and mouth disease (HFMD) caused by human enterovirus 71 (EV71...
...vaccine within 4-5 months after commercial production starts. Sinovac Biotech Ltd. (NASDAQ:SVA), Beijing, China Product: EV71...
BioCentury | May 5, 2014
Company News

Sinovac infectious news

...RMB60 million ($9.6 million) grant to construct a production facility for its human enterovirus 71 (EV71...
BioCentury | Mar 10, 2014
Clinical News

EV71 vaccine: Final Phase III data

...disease (HFMD) caused by EV71 Endpoint: Incidence of disease at 1 year after final dose; anti-EV71...
...showed that Sinovac's EV71 vaccine significantly reduced the incidence of HFMD or herpangina caused by EV71...
...in the EV71 vaccine arm vs. 19.3 in the placebo arm. Additionally, the vaccine prevented EV71-associated...
BioCentury | Sep 19, 2013
Distillery Techniques

Technology: Disease models

...Disease models Transgenic scavenger receptor class B member 2 (SCARB2) mice to model enterovirus 71 (EV71...
...neuropathogenesis Transgenic mice that express human SCARB2 could be useful for studying the neuropathogenesis of EV71...
...murine CNS tissues. In transgenic mice expressing SCARB2, a known receptor for EV71, infection with EV71...
BioCentury | Jun 3, 2013
Finance

Highlights of weekly biotech stock moves

...Drug Administration for a vaccine against hand, foot and mouth disease caused by enterovirus 71 (EV71...
BioCentury | Jun 3, 2013
Clinical News

EV71 vaccine regulatory update

...its EV71 vaccine against hand, foot and mouth disease (HFMD) caused by human enterovirus 71 (EV71...
...necessary approvals" to launch the vaccine in 2014. Sinovac Biotech Ltd. (NASDAQ:SVA), Beijing, China Product: EV71...
BioCentury | May 13, 2013
Company News

Inviragen, Takeda deal

...year. The company's clinical pipeline also includes INV21 , an inactivated whole enterovirus 71 ( EV71...
...has completed Phase I testing to vaccinate against hand, foot and mouth disease caused by EV71...
BioCentury | May 9, 2013
Company News

Takeda acquiring Inviragen

...this year. The company's clinical pipeline also includes INV21 , an inactivated whole enterovirus 71 (EV71...
...completed Phase I testing to vaccinate against hand, foot and mouth disease (HFMD) caused by EV71...
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