BioCentury | Jun 4, 2020
Product Development

With impending Benlysta submission, GSK seeking new paradigm in lupus nephritis treatment

...drug mycophenolate plus “industrial-strength” steroids; response rates are typically in the mid-30% range. Chemotherapy drug cyclophosphamide...
BioCentury | Mar 27, 2020
Regulation

CHMP decisions set stage for approval of Novartis’ SMA gene therapy, Celgene’s Zeposia for MS, Sanofi’s comeback cancer drug

...Tokyo:4502; NYSE:TAK) for first-line treatment of systemic anaplastic large cell lymphoma (sALCL) in combination with cyclophosphamide...
BioCentury | Sep 20, 2019
Company News

China exempts 12 cancer drugs from tariffs

...Co. Ltd. (Tokyo, Japan); Conmana icotinib from Beta Pharma (Princeton, N.J.); as well as floxuridine, cyclophosphamide...
...Assistant Editor and Hongjiang Li, Staff Writer Iressa, gefitinib (ZD1839) Xeloda, capecitabine (R340, RG340) AstraZeneca plc Otsuka Pharmaceutical Co. Ltd. Roche floxuridine cyclophosphamide tegafur ifosfamide...
BioCentury | Mar 7, 2019
Translation in Brief

Blocking B cell vesicles to enhance chemotherapy

...antitumor effect of chemotherapy. In a xenograft mouse model of colorectal cancer, the generic chemotherapy cyclophosphamide...
BioCentury | Feb 28, 2019
Distillery Therapeutics

Cancer

...survival. In a xenograft mouse model of colorectal cancer, IV injection of the generic chemotherapy cyclophosphamide...
...factor required for extracellular vesicle formation - decreased tumor growth and increased survival compared with cyclophosphamide...
BioCentury | Dec 14, 2018
Clinical News

Adcetris improves PFS by 27.4 months in first-line PTCL

...Independent Central Review (BICR) by 27.4 months at a median follow-up of 36.2 months vs. cyclophosphamide...
BioCentury | Oct 5, 2018
Clinical News

Adcetris meets in Phase III for first-line PTCL

...endpoint, Adcetris plus cyclophosphamide, doxorubicin and prednisone (CHP) chemotherapy significantly improved progression-free survival (PFS) vs. cyclophosphamide...
BioCentury | Sep 28, 2018
Clinical News

Cell Medica doses first neuroblastoma patient with NK cell therapy

...6 , 1x10 7 , 3x10 7 or 1x10 8 CMD-501 cells in combination with cyclophosphamide...
BioCentury | Aug 8, 2018
Emerging Company Profile

Catching antibodies with polymers

...for anti-MAG neuropathy, Rituxan rituximab from the Genentech Inc. unit of Roche and Biogen Inc., cyclophosphamide...
...with IVIG or cyclophosphamide with very little, only transient, or no improvements at all” and cyclophosphamide...
BioCentury | Jul 6, 2018
Clinical News

Spectrum's Rolontis meets in second Phase III for chemotherapy-induced neutropenia

...Phase III RECOVER trial in 237 early stage breast cancer patients who received docetaxel and cyclophosphamide...
...the Phase III ADVANCE trial in early stage breast cancer patients who received docetaxel and cyclophosphamide...
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