21:26 , Jul 25, 2019 |  BC Innovations  |  Distillery Therapeutics

Inhibiting PARP for pathologic vascular calcification

DISEASE CATEGORY: Cardiovascular INDICATION: Cardiovascular PARP inhibition could treat pathologic vascular calcifications. In patients with carotid artery disease, sites of calcification within atherosclerotic plaques and blood vessel tunica media had higher extranuclear deposition of PARP-synthesized...
02:49 , Jan 5, 2019 |  BioCentury  |  Finance

Ready to launch

  The proposed $74 billion takeout of Celgene Corp. by Bristol-Myers Squibb Co. will not shift buysider attention away from upcoming and maturing drug launches heading into 2019, with plenty to track following a record...
17:57 , Nov 9, 2018 |  BC Week In Review  |  Clinical News

Foamix planning NDA for minocycline foam to treat rosacea

Foamix Pharmaceuticals Ltd. (NASDAQ:FOMX) plans to submit an NDA to FDA next year for FMX103 to treat moderate to severe papulopustular rosacea after the product met the co-primary endpoints in a pair of Phase III...
11:00 , Nov 7, 2018 |  BC Extra  |  Clinical News

Foamix planning NDA for minocycline foam to treat rosacea

Foamix Pharmaceuticals Ltd. (NASDAQ:FOMX) plans to submit an NDA to FDA next year for FMX103 to treat moderate to severe papulopustular rosacea after the product met the co-primary endpoints in a pair of Phase III...
15:56 , Oct 26, 2018 |  BioCentury  |  Finance

Rempex remix

New Enterprise Associates led Qpex Biopharma Inc.’s $33 million A round in hope that the management team will repeat its performance at Rempex Pharmaceuticals Inc. and The Medicines Co. (NASDAQ:MDCO) with a preclinical anti-infectives portfolio....
18:02 , Oct 25, 2018 |  BC Innovations  |  Distillery Therapeutics

Neurology

INDICATION: Cognitive dysfunction Mouse studies suggest inhibiting microglial activation could help treat obesity-associated cognitive dysfunction. In hippocampal tissue from a mouse model of obesity-associated cognitive dysfunction, microglia activation scores were higher than in normal mice....
17:27 , Sep 14, 2018 |  BC Week In Review  |  Clinical News

Foamix's minocycline foam meets in third Phase III for acne

Foamix Pharmaceuticals Ltd. (NASDAQ:FOMX) reported on Sept. 11 that FMX101 met the co-primary endpoints in the Phase III FX2017-22 trial to treat moderate to severe acne. By year end, the company plans to submit an...
13:20 , Sep 14, 2018 |  BC Extra  |  Financial News

Foamix raises $70M following Phase III acne readout

Foamix Pharmaceuticals Ltd. (NASDAQ:FOMX) raised $70 million through the sale of 11.7 million shares at $6 in a follow-on underwritten by BofA Merrill Lynch, Cowen, Barclays and Cantor Fitzgerald. The price is a tiny discount...
19:32 , Sep 10, 2018 |  BC Innovations  |  Distillery Therapeutics

Neurology

INDICATION: Encephalopathy Patient sample and mouse studies suggest inhibiting the JAK/STAT1 pathway, the interaction between MCP-1 and CCR2, or phagocyte activation could help treat Rasmussen encephalitis. In postmortem brain samples from patients, levels of phosphorylated...
03:04 , Jun 30, 2018 |  BioCentury  |  Finance

Eyes on launches

The annual summer slowdown isn’t restricted to just the stock market this year, as the clinical catalyst calendar also appears to be on holiday in 3Q18. Buysiders are therefore turning their attention to a spate...