BC Innovations | Dec 11, 2019
Product Development

The writing has been on the wall for Sanofi’s diabetes, CV business for years

One hundred days after taking the helm as CEO, Paul Hudson has outlined a plan to get Sanofi to 30% margins by 2022 that hinges largely on the success of Dupixent and five other priority...
BC Extra | Sep 26, 2019
Politics & Policy

MNCs gain ground in China’s centralized procurement

Five multinational originator companies were among the winning bidders in China’s national expansion of its centralized procurement program for generic and off-patent drugs in a process that saw steep price cuts and more robust participation...
BC Week In Review | Feb 1, 2019
Company News

AZ, UPMC in value-based agreement for Brilinta

To reduce out-of-pocket costs for Medicare patients, AstraZeneca plc (LSE:AZN; NYSE:AZN) signed a value-based contract with UPMC Health Plan for Brilinta ticagrelor that links reimbursement of the drug to cardiovascular outcomes following a recent hospitalization...
BC Extra | Jan 28, 2019
Company News

AZ, UPMC in value-based agreement for Brilinta

To reduce out-of-pocket costs for Medicare patients, AstraZeneca plc (LSE:AZN; NYSE:AZN) signed a value-based contract with UPMC Health Plan for Brilinta ticagrelor that links reimbursement of the drug to cardiovascular outcomes following a recent hospitalization...
BC Week In Review | Dec 21, 2018
Clinical News

Idorsia's P2RY12 antagonist inhibits platelet aggregation within 15 minutes

Idorsia Ltd. (SIX:IDIA) said single subcutaneous injections of selatogrel (ACT-246475) inhibited platelet aggregation within 15 minutes with its maximum effect extending over 4-8 hours depending on the dose in a pair of Phase II trials...
BioCentury | Sep 2, 2017
Strategy

Back to School: Breach of contract

Merck & Co. Inc. Chairman and CEO Kenneth Frazier’s resignation in August from a White House advisory council was an act of principle, and a reminder that 30 years ago Merck was one of the...
BC Extra | Jun 19, 2017
Politics & Policy

SCOTUS sides with BMS in jurisdictional case

In an 8-1 decision Monday, the U.S. Supreme Court ruled that out-of-state residents could not enter a case brought against Bristol-Myers Squibb Co. (NYSE:BMY) in California, reversing an earlier state court's decision that BMS's "extensive...
BC Week In Review | Jun 2, 2017
Company News

AZ and Harvard Pilgrim sign two outcomes-based drug pricing contracts

Regional insurer Harvard Pilgrim Health Care Inc. (Boston, Mass.) signed two outcomes-based drug pricing contracts with AstraZeneca plc (LSE:AZN; NYSE:AZN). The insurer signed a three-year contract for AZ’s Brilinta ticagrelor, which is marketed in the...
BC Week In Review | Mar 31, 2017
Clinical News

Xarelto: Ph II GEMINI-ACS-1 data

The double-blind, international Phase II GEMINI-ACS-1 trial in 3,037 patients with ACS showed that twice-daily 2.5 mg oral Xarelto plus clopidogrel or Brilinta ticagrelor led to no significant difference in the rate of TIMI clinically...
BC Week In Review | Mar 14, 2017
Clinical News

Savaysa: Ph IIIb ENTRUST-AF PCI started

Daiichi began the open-label, international Phase IIIb ENTRUST-AF PCI trial to evaluate 30 and 60 mg oral Savaysa once daily vs. a vitamin K antagonist for 12 months in 1,500 patients. Patients will also receive...
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