BioCentury | Sep 11, 2019
Translation in Brief

Cold Spring Harbor team finds off-target activity can drive antitumor effects

...the clinic, and at least one remains in development cancer. According to ClinicalTrials.gov, HDAC6 inhibitor citarinostat...
BioCentury | Apr 10, 2018
Distillery Therapeutics

Autoimmune disease

...also have the compound in preclinical testing for chemotherapy-induced peripheral neuropathy (CIPN). Celgene has citarinostat (ACY-241...
BioCentury | Jan 27, 2018
Strategy

Jump-starting growth

...Ig and ITIM domains (TIGIT) Solid tumors (Ph I) OncoMed Pharmaceuticals Inc. (NASDAQ:OMED) (B) Citarinostat (ACY-241...
BioCentury | Oct 24, 2017
Distillery Therapeutics

Neurology

...HDAC6 inhibitors in mouse models of ALS. Celgene Corp. has two oral HDAC6 inhibitors: citarinostat (ACY-241...
BioCentury | Dec 9, 2016
Company News

Acetylon, Celgene deal

...Celgene will gain rights to Acetylon's lead candidates, oral HDAC6 inhibitors ricolinostat (ACY-1215) and citarinostat (ACY-241...
...Both are in development for multiple myeloma (MM); ricolinostat is in Phase I testing and citarinostat...
...Acetylon Pharmaceuticals Inc. , Boston, Mass. Celgene Corp. (NASDAQ:CELG), Summit, N.J. Business: Cancer, Neurology, Autoimmune Alicia Parker ACY-1215 ACY-241 citarinostat ricolinostat Acetylon...
BioCentury | Dec 3, 2016
Company News

Celgene acquiring Acetylon after spinout of newco

...rights to Acetylon's lead candidates, oral HDAC6 inhibitors ricolinostat ( ACY-1215 ) and citarinostat ( ACY-241...
...Acetylon announced the deal during market hours. Celgene lost $1.24 to $117.63 on Friday. Becky Simon ACY-1215 ACY-241 HDAC...
BioCentury | Dec 21, 2015
Clinical News

ACY-241: Preliminary Phase I data

...a proteasome inhibitor in the open-label, U.S. Phase Ia/Ib ACE-MM-200 trial showed that once-daily oral ACY-241...
...response, 1 unconfirmed partial response and 1 minor response, plus 2 cases of stable disease. ACY-241...
...the American Society of Hematology meeting in Orlando. Acetylon Pharmaceuticals Inc. , Boston, Mass. Product: ACY-241...
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