BioCentury | Aug 30, 2019
Politics & Policy

Industry group responds to Dutch Minister’s 'something’s gotta give' reaction to drug price increases

...At least one price hike in the last two years could fit Bruins' description. Chenodiol chenodeoxycholic acid...
...a target of local manufacturing. In a 2018, the Amsterdam Medical Center produced its own chenodeoxycholic acid...
...Leadiant. However, production has been suspended due to concerns about product quality. Inhua Muijrers-Chen, Associate Editor Chenodiol (chenodeoxycholic acid...
BioCentury | Aug 22, 2019
Clinical News

After neurodegeneration miss, Retrophin looks to rebound with renal program

...data from DUPLEX and PROTECT in 1H21 and 1H22, respectively. Retrophin markets three drugs: Chenodal chenodeoxycholic acid...
BioCentury | Aug 23, 2018
Distillery Therapeutics

Gastrointestinal

...increased crypt proliferation and regeneration compared with vehicle. Also in the model, the FXR agonist chenodeoxycholic acid...
BioCentury | Jun 13, 2018
Distillery Therapeutics

Cancer

...metastases, compared with vehicle. Also in the melanoma model, vancomycin plus the primary bile acid chenodeoxycholic acid...
...models. Leadiant Biosciences S.p.A. markets Chenodiol chenodeoxycholic acid to treat cerebrotendinous xanthomatosis. Retrophin Inc. markets Chenodal chenodeoxycholic acid...
BioCentury | Mar 17, 2017
Company News

Retrophin restructuring news

...disorders due to single enzyme defects and as adjunctive treatment of peroxisomal disorders; and Chenodal chenodeoxycholic acid...
...12-month operating loss of $58.2 million. Retrophin Inc. (NASDAQ:RTRX), San Diego, Calif. Business: Renal, Gastrointestinal Chris Lieu Chenodal Cholbam Thiola Retrophin...
BioCentury | Sep 26, 2016
Clinical News

Chenodeoxycholic acid regulatory update

...EMA’s CHMP recommended approval of chenodeoxycholic acid from Sigma-Tau to treat cerebrotendinous xanthomatosis. The naturally occurring bile...
...as Xenbilox in the EU to treat gall stones. Sigma-Tau Group , Pomezia, Italy Product: Chenodeoxycholic acid...
BioCentury | Feb 4, 2016
Distillery Therapeutics

Therapeutics: Farnesoid X receptor (FXR; NR1H4)

...MS. In the experimental autoimmune encephalomyelitis (EAE) mouse model of MS, the endogenous FXR ligand chenodeoxycholic acid...
...Phase II testing to treat biliary atresia and primary sclerosing cholangitis. Retrophin Inc. markets Chenodal chenodeoxycholic acid...
...has the compound in Phase III testing to treat cerebrotendinous xanthomatosis (CTX). Sigma-Tau Group markets chenodeoxycholic acid...
BioCentury | Aug 11, 2014
Company News

Clinuvel, Retrophin deal

...rare disease company Manchester Pharmaceuticals LLC and gained two products marketed in the U.S.: Chenodal chenodeoxycholic acid...
BioCentury | Feb 17, 2014
Company News

Manchester Pharmaceuticals, Retrophin deal

...up front, plus undisclosed royalties. Retrophin will gain two products marketed in the U.S.: Chenodal chenodeoxycholic acid...
...cases of malignant hypertension. Retrophin said it plans to seek FDA approval this year of Chenodal...
BioCentury | Feb 17, 2014
Finance

Highlights of weekly biotech stock moves

...front, plus undisclosed royalties. Retrophin will gain two products marketed in the U.S., including Chenodal chenodeoxycholic acid...
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