07:00 , Apr 10, 2014 |  BC Innovations  |  Cover Story

Pre-EMP-tive strike against GBM

University of California, Los Angeles researchers have treated glioblastoma in mice by inhibiting epithelial membrane protein 2 . 1 The findings open up a new indication for spinout Paganini Biopharma Inc. , which has a...
08:00 , Jan 12, 2012 |  BC Innovations  |  Distillery Therapeutics

Indication: Cancer

Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Cancer Focal adhesion kinase (FAK) Cell culture studies suggest combining FAK and autophagy inhibitors could help treat cancer. In squamous carcinoma cells from Fak knockout...
08:00 , Jan 5, 2012 |  BC Innovations  |  Distillery Therapeutics

Indication: Dermatology

Indication Target/marker/pathway Summary Licensing status Publication and contact information Dermatology Scars/wrinkles Focal adhesion kinase (FAK) Mouse studies suggest topical FAK inhibitors could help prevent dermal scarring. In a mouse model of cutaneous scarring, a topical...
07:00 , Apr 25, 2011 |  BioCentury  |  Product Development

In with the ALK Crowd

Pfizer Inc. 's crizotinib has provided POC that targeting ALK can significantly improve response in a small subset of non-small cell lung cancer patients compared to current treatments. While the pharma completes it NDA submission,...
07:00 , Apr 4, 2011 |  BC Week In Review  |  Company News

Cephalon, Champions Biotechnology deal

Champions will use its Biomerk Tumorgraft technology to evaluate the efficacy of Cephalon's CEP-37440 for cancer. The Tumorgraft technology uses implantation of human tumors in immune deficient mice to predict therapeutic response to potential cancer...
07:00 , Apr 4, 2011 |  BioCentury  |  Strategy

Half-A-Loaf Dilemma

Cephalon Inc. 's board is evaluating the two options in last week's hostile takeover bid from Valeant Pharmaceuticals International Inc. : take the $5.7 billion in cash for the whole company, or take $2.8 billion...
08:00 , Mar 10, 2011 |  BC Innovations  |  Distillery Therapeutics

Indication: Cancer

Indication Target/marker/ pathway Summary Licensing status Publication and contact information Cancer Cancer Focal adhesion kinase (FAK) A study in mice suggests that inhibiting FAK could help prevent metastasis. In mice with cancer, expression of nonfunctional...