07:00 , Apr 10, 2014 |  BC Innovations  |  Cover Story

Pre-EMP-tive strike against GBM

University of California, Los Angeles researchers have treated glioblastoma in mice by inhibiting epithelial membrane protein 2.1 The findings open up a new indication for spinout Paganini Biopharma Inc., which has a mAb against the...
08:00 , Jan 12, 2012 |  BC Innovations  |  Distillery Therapeutics

Indication: Cancer

Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Cancer Focal adhesion kinase (FAK) Cell culture studies suggest combining FAK and autophagy inhibitors could help treat...
08:00 , Jan 5, 2012 |  BC Innovations  |  Distillery Therapeutics

Indication: Dermatology

Indication Target/marker/pathway Summary Licensing status Publication and contact information Dermatology Scars/wrinkles Focal adhesion kinase (FAK) Mouse studies suggest topical FAK inhibitors could help prevent dermal scarring. In...
07:00 , Apr 25, 2011 |  BioCentury  |  Product Development

In with the ALK Crowd

Pfizer Inc.'s crizotinib has provided POC that targeting ALK can significantly improve response in a small subset of non-small cell lung cancer patients compared to current treatments. While the pharma completes it NDA submission, other...
07:00 , Apr 4, 2011 |  BC Week In Review  |  Company News

Cephalon, Champions Biotechnology deal

Champions will use its Biomerk Tumorgraft technology to evaluate the efficacy of Cephalon's CEP-37440 for cancer. The Tumorgraft technology uses implantation of human tumors in immune deficient mice to predict therapeutic response to potential...
07:00 , Apr 4, 2011 |  BioCentury  |  Strategy

Half-A-Loaf Dilemma

Cephalon Inc.'s board is evaluating the two options in last week's hostile takeover bid from Valeant Pharmaceuticals International Inc.: take the $5.7 billion in cash for the whole company, or take $2.8 billion for the...
08:00 , Mar 10, 2011 |  BC Innovations  |  Distillery Therapeutics

Indication: Cancer

Indication Target/marker/ pathway Summary Licensing status Publication and contact information Cancer Cancer Focal adhesion kinase (FAK) A study in mice suggests that inhibiting FAK could help prevent...