BioCentury | Dec 11, 2014
Targets & Mechanisms

Lysin in wait

...antibiotic Centany mupirocin or Staphefekt developed resistance to the antibiotic but not to Staphefekt. 2 Centany...
BioCentury | Mar 11, 2013
Product Development

Neomics' new tricks

...to target bacterial ARSs with antibiotics, but other than GlaxoSmithKline plc 's marketed antibiotic Bactroban mupirocin...
BioCentury | Jul 4, 2011
Emerging Company Profile

ContraFect: Bringing down the walls

...year in Antimicrobial Agents and Chemotherapy , the Rockefeller group showed that staph lysin plus mupirocin...
...standard agent for treating methicillin-resistant S. aureus (MRSA) - was capable of killing MRSA and mupirocin-resistant...
BioCentury | Jan 6, 2011
Distillery Therapeutics

Indication: Infectious disease

...an engineered lysin protein that degrades bacterial cell walls, lowered levels of infection compared with mupirocin...
...GMP production of ClyS and safety and toxicity studies in mice and mini pigs. Bactroban mupirocin...
BioCentury | Apr 10, 2008
Targets & Mechanisms

Staph: The NOse Have It

...settings," he said. According to Fang, current treatment for nasal staph infectioninvolves a course of mupirocin...
...many patients do not stick to the multiweek regimen. Also, MRSA strains are resistant to mupirocin...
BioCentury | Dec 10, 2007
Clinical News

Phynova preclinical data

...30 common strains of MRSA bacteria at doses that were 10-fold less the topical antibiotic mupirocin...
BioCentury | Aug 14, 2006
Tools & Techniques

More pep against infection

...that incorporates CSA-13. The ointment will be used as a replacement for the topical antibiotic mupirocin...
...partners before starting clinical testing of CSA-13 and CSA-54. It will develop Cerashield and the mupirocin...
BioCentury | Jul 24, 2006
Clinical News

REP8839: Phase I started

...RDYN began a placebo-controlled Phase I trial of REP8839 in combination with topical antibiotic mupirocin in...
BioCentury | Sep 19, 2005
Finance

Ebb & Flow

...slated to enter the clinic early next year. It is a topical analog of Bactroban mupirocin...
BioCentury | Jun 17, 2002
Clinical News

Bactroban Nasal mupirocin ointment: Marketed to eradicate nasal colonization with methicillin-resistant S. aureus

...In a double-blind, placebo-controlled MARS trial in 3,864 evaluable patients, preoperative intranasal application of mupirocin did...
...the New England Journal of Medicine. GlaxoSmithKline plc (GSK; LSE:GSK), London, U.K. Product: Bactroban Nasal mupirocin...
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