15:43 , Sep 27, 2018 |  BC Innovations  |  Distillery Therapeutics

Cancer

INDICATION: Multiple myeloma (MM) Patient sample, cell culture and mouse studies suggest antagonizing AHR could help treat MM. In patients, high tumor levels of AHR correlated with poor survival. In multiple Velcade bortezomib-resistant and -sensitive...
08:00 , Feb 29, 2016 |  BioCentury  |  Emerging Company Profile

Hercules' IDO alternative

Hercules Pharmaceuticals B.V. is developing an inhibitor of aryl hydrocarbon receptor that taps into the same pathway as IDO and TDO inhibitors but could improve upon their tolerability while delivering similar efficacy. Improved tolerability could...