BioCentury | Apr 29, 2020
Product Development

Thrive AACR data highlights specificity, sensitivity trade-offs for cancer screening

Data from Thrive’s prospective, multicancer blood test study makes it clear that avoiding false positives is the top priority when screening asymptomatic individuals for rare events. While that inevitably comes at the cost of sensitivity,...
BC Innovations | Aug 15, 2019
Product Development

Adaptive is surfing a wave of enthusiasm in disease detection, betting on the immune system

Adaptive’s float to more than $5 billion after its June IPO is largely based on its ambition to compete with the likes of Grail and Guardant in early diagnosis of cancer and other diseases by...
BC Extra | May 31, 2019
Clinical News

Grail unveils competitive ASCO data from second substudy of CCGA trial

Just a day after the launch of the latest liquid biopsy company, data from Grail show it will be a tight race to develop a multicancer liquid biopsy test for early cancer detection -- and...
BioCentury | May 30, 2019
Emerging Company Profile

Thrive’s quest to bring multicancer liquid biopsy test into routine clinical use

With Third Rock leading the way in a $110 million series A, newly launched Thrive is banking that a multi-analyte approach to liquid biopsy could give it an edge in creating a test that is...
BC Innovations | Jan 23, 2018
Distillery Techniques

Assays and screens

TECHNOLOGY: Diagnostic assays; cell-free assays; plasma assays A method for detecting circulating tumor-derived cfDNA and proteins could help diagnose eight types of solid cancers. The method, dubbed CancerSEEK, has two parts: the combination of a...
BC Extra | Jan 18, 2018
Preclinical News

Blood-based test analyzes cfDNA, protein biomarkers for earlier cancer detection

In a study published in Science , researchers from Johns Hopkins University describe the development of CancerSEEK, a diagnostic that could enable earlier blood-based cancer detection by analyzing both cell-free DNA (cfDNA) and circulating protein biomarkers....
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