07:00 , Aug 15, 2016 |  BioCentury  |  Emerging Company Profile

Restraining translation

Bantam Pharmaceutical LLC is developing small molecule eukaryotic translation initiation factor 4E inhibitors that selectively inhibit translation of several tumor-promoting genes and disrupt cancer cell metabolism. It hopes to show the mechanism of its lead...
07:00 , Aug 11, 2011 |  BC Innovations  |  Distillery Therapeutics

Indication: Cancer

Indication Target/marker/ pathway Summary Licensing status Publication and contact information Cancer Mantle cell lymphoma (MCL) Cyclin D1 (CCND1; BCL1); B cell lymphoma 2 (BCL-2; BCL2) Studies in cell culture suggest combining CCND1 and BCL2 inhibitors...