BioCentury | Nov 16, 2017
Translation in Brief

Lighting up the DYRK

...the mother and the difficulties involved in running prenatal clinical trials. Roche (SIX:ROG; OTCQX:RHHBY) had RG1662...
BioCentury | Feb 5, 2015
Product R&D

Addex's allosterics

...NMDA receptor PAM and selective norepinephrine reuptake inhibitor Phase II Schizophrenia None Roche (SIX:ROG; OTCQX:RHHBY) RG1662...
BioCentury | Sep 26, 2013
Targets & Mechanisms

Hedgehog battles Down syndrome

...develops more rapidly in patients with Down syndrome than in healthy controls. For example, Roche's RG1662...
BioCentury | Mar 7, 2013
Distillery Therapeutics

Indication: Neurology

...induce anxiety-like behaviors or convulsions. Next steps include additional preclinical studies with RO4938581. Roche has RG1662...
BioCentury | Mar 4, 2013
Clinical News

Roche preclinical data

...Roche said is only being used for preclinical testing. The pharma's clinical GABRA5 inhibitor - RG1662...
...are expected to complete this year. F. Hoffmann-La Roche Ltd. (SIX:ROG; OTCQX:RHHBY), Basel, Switzerland Product: RG1662...
BioCentury | Oct 22, 2012
Clinical News

RG1662: Phase I started

...trial evaluating RG1662 in 17 patients and healthy volunteers. Roche (SIX:ROG; OTCQX:RHHBY), Basel, Switzerland Product: RG1662...
BioCentury | Oct 22, 2012
Clinical News

RG1662: Phase I started

...of RG1662 over 28 days in 6 healthy volunteers. Roche (SIX:ROG; OTCQX:RHHBY), Basel, Switzerland Product: RG1662...
BioCentury | Oct 8, 2012
Product Development

Contrarian thinking

...Ph II pRED RG7129 Inhibitor of beta-site APP- cleaving enzyme (BACE) AD Ph I pRED RG1662...
BioCentury | Sep 19, 2011
Clinical News

RG1662: Phase I started

...Roche began a double-blind, placebo-controlled Phase I trial to evaluate multiple doses of oral RG1662 for...
...days in about 33 Down syndrome patients ages 18-30. Roche (SIX:ROG; OTCQX:RHHBY), Basel, Switzerland Product: RG1662...
BioCentury | Oct 21, 2010
Distillery Therapeutics

Indication: Neurology

...that selectively modulate GABAA signaling in the dentate gyrus, a brain region implicated in AD. RG1662...
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