BioCentury | May 26, 2020
Distillery Therapeutics

Targeting the super elongation complex for diffuse midline glioma

...CDK9 inhibitors alvocidib, atuveciclib or AZD4573 reduced proliferation. In a xenograft mouse model, atuveciclib and AZD4573...
...Xetra:BAYN) has atuveciclib in Phase I testing for acute leukemia. AstraZeneca plc (LSE:AZN; NYSE:AZN) has AZD4573...
...CONTACT: Rajeev Vibhakar, same affiliation as above email: rajeev.vibhakar@ucdenver.edu Claire Quang alvocidib, flavopiridol (DSP-2033, hmr 1275) Atuveciclib (BAY 1143572) AZD4573 University...
BioCentury | Nov 9, 2018
Distillery Therapeutics

Cancer

...oral prodrug of alvocidib, in preclinical testing for AML and solid tumors. AstraZeneca plc has AZD4573...
BioCentury | Nov 8, 2018
Translation in Brief

Solid plans for CDK9

...and Phase II testing for AML and myelodysplastic syndrome (MDS). AstraZeneca plc (LSE:AZN; NYSE:AZN) has AZD4573...
BioCentury | Mar 20, 2018
Distillery Therapeutics

Cancer; autoimmune disease

...and chronic lymphocytic leukemia (CLL) and preclinical testing for myelodysplastic syndrome (MDS). AstraZeneca plc has AZD4573...
BioCentury | Mar 20, 2018
Distillery Therapeutics

Cancer

...oral prodrug of alvocidib, in preclinical testing for AML and solid tumors. AstraZeneca plc has AZD4573...
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