08:00 , Feb 26, 2007 |  BC Week In Review  |  Clinical News

AVE0675: Phase I start

SAN will start a Phase I trial of inhaled AVE0675. In January, the FDA lifted a clinical hold that had been placed on the IND in 2005. SAN licensed rights to four TLR programs, including...
07:00 , Aug 15, 2005 |  BioCentury  |  Tools & Techniques

Tallying TLRs

Tallying TLRs Company Product Partner Description Indication Status 3M Aldara imiquimod None Topical TLR7 agonist Genital warts, basal cell carcinoma(BCC) and actinic keratosis Mkt Undisclosed Takeda Topical TLR7 agonist Cervical high-risk human papillomavirus (HPV) infection...
07:00 , Aug 15, 2005 |  BioCentury  |  Tools & Techniques

The toll collectors

Immune modulation should be a subtle activity, as the name implies. But existing immunomodulatory drugs are like using a sledgehammer to hit a tack, and the side effects of drugs like interferon alpha and IL-2...