07:00 , Aug 8, 2013 |  BC Innovations  |  Distillery Therapeutics

Indication: Infectious disease

Indication Target/marker/pathway Summary Licensing status Publication and contact information Infectious disease Sepsis Angiopoietin 2 (ANG2; ANGPT2) Mouse studies suggest inhibiting ANG2 could help treat sepsis. ANG2 is upregulated during sepsis. In mice, endothelium-specific ANG2 overexpression...
08:00 , Dec 13, 2012 |  BC Innovations  |  Tools & Techniques

Pulmonary edema on a chip

Researchers at the Harvard University have described the first disease model to emerge from the institute's organ-on-a-chip microfluidic device technology. 1,2 The model of pulmonary edema could be better than culture models at predicting whether...
07:00 , Sep 17, 2012 |  BC Week In Review  |  Clinical News

Silence Therapeutics preclinical data

In a preclinical model of Streptococcus pneumonia acute lung injury, Atu111 plus antibiotic therapy led to a 90% survival benefit vs. untreated controls, while antibiotic therapy alone led to a 20% benefit vs. controls. The...