BioCentury | Apr 21, 2016
Translation in Brief

Arginine and TH17 in lupus

...converts arginine into ornithine and urea and influences diverse immune pathways. Mars Symbioscience has an arginase inhibitor...
BioCentury | Apr 23, 2015
Distillery Therapeutics

Therapeutics: Arginase 1 (ARG1)

Neurology INDICATION: Alzheimer's disease (AD) Mouse studies suggest inhibiting arginase could help treat AD. In pathological brain tissue of a mouse model of AD, levels of ARG1 were higher and levels of arginine were lower...
BioCentury | Jan 26, 2015
Company News

Mars Symbioscience, Calithera Biosciences deal

...the program will help it submit an IND to FDA by year end for an arginase inhibitor...
BioCentury | Jun 21, 2010

Friendly persuasion

...from Immune Control, into a Phase I trial in late 2010 or early 2011. Arginetix's arginase inhibitor...
BioCentury | Jun 21, 2010
Company News

Arginetix, Immune Control deal

...IND filing planned for next half. Corridor also will have access to Arginetix's small molecule arginase inhibitor...
BioCentury | Dec 7, 2009
Emerging Company Profile

Another NO to PAH: Sidebar: Corporate Profile

Arginetix Inc. Baltimore, Md. Technology: Small molecule arginase inhibitors Disease focus: Cardiovascular, inflammation Clinical status: Preclinical Founded: 2007 by Gary Lessing, Dan Berkowitz and David Christianson University collaborators: University of Pennsylvania and Johns Hopkins University...
BioCentury | Dec 7, 2009
Emerging Company Profile

Arginetix: Another NO to PAH

...Groningen reported in the American Journal of Respiratory and Critical Care Medicine that an inhaled arginase inhibitor...
...of Applied Physiology , J.H. Kim and colleagues from Johns Hopkins University showed that an arginase inhibitor...
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