BC Week In Review | Jun 2, 2014
Company News

Reckitt Benckiser, XenoPort deal

XenoPort granted Reckitt an exclusive, worldwide license to develop and commercialize arbaclofen placarbil ( XP19986 ). XenoPort will have certain rights to negotiate with Reckitt on collaborations for non-addiction indications. Reckitt plans to begin a Phase...
BC Week In Review | May 27, 2013
Clinical News

Arbaclofen placarbil: Development discontinued

Xenoport discontinued development of arbaclofen placarbil after top-line data from a 13-week, double-blind, U.S. Phase III trial in 228 patients with spasticity due to MS showed that the product missed the co-primary endpoints of improving...
BC Week In Review | Apr 15, 2013
Clinical News

Arbaclofen placarbil: Completed Phase III enrollment

XenoPort disclosed in its 4Q12 earnings that it completed enrollment in a double-blind, placebo-controlled, U.S. Phase III trial evaluating twice-daily 15, 30 and 45 mg arbaclofen placarbil for 13 weeks in about 200 patients. Patients...
BC Week In Review | Aug 8, 2011
Clinical News

Arbaclofen placarbil: Phase III started

XenoPort disclosed in its 2Q11 earnings that it began a double-blind, placebo-controlled, U.S. Phase III trial to evaluate twice-daily 15, 30 and 45 mg arbaclofen placarbil for 13 weeks in about 200 patients. Patients will...
BC Week In Review | May 2, 2011
Clinical News

Arbaclofen placarbil: SPA received

XenoPort received an SPA from FDA for a planned double-blind, placebo-controlled, U.S. Phase III trial to evaluate twice-daily 15, 30 and 45 mg arbaclofen placarbil for 13 weeks in about 200 patients. The Phase III...
BC Week In Review | Mar 28, 2011
Clinical News

Arbaclofen placarbil: Preliminary Phase IIb data

XenoPort discontinued development of arbaclofen placarbil to treat GERD after top-line data from a double-blind, North American Phase IIb trial in 460 patients who remained symptomatic despite PPI treatment showed that all doses of the...
BC Week In Review | Nov 15, 2010
Clinical News

Arbaclofen placarbil: Completed Phase IIb enrollment

XenoPort disclosed in its 3Q10 earnings that it completed enrollment of 425 patients in a double-blind, placebo-controlled, North American Phase IIb trial evaluating arbaclofen placarbil at doses of 20 or 30 mg twice daily or...
BC Week In Review | Sep 20, 2010
Clinical News

Arbaclofen placarbil: Phase III start

After discussions with FDA, XenoPort said it plans to start a placebo-controlled Phase III trial and a long-term, open-label safety study of arbaclofen placarbil in 1H11. XenoPort said it hopes the studies will support the...
BioCentury | Sep 20, 2010
Finance

Regulatory Milestones

Alkermes Inc. (NASDAQ:ALKS) was up $0.89 to $14.87 last week after FDA's Psychopharmacologic Drugs Advisory Committee voted 12-1 to recommend approval of an sNDA to extend the label of Vivitrol naltrexone to prevent relapse to...
BC Extra | Sep 14, 2010
Clinical News

XenoPort up on arbaclofen placarbil plans

XenoPort Inc. (NASDAQ:XNPT) gained $1.35 (22%) to $7.55 on Monday after announcing plans to start Phase III testing in 1H11 for arbaclofen placarbil ( XP19986 ) to treat spasticity in multiple sclerosis (MS) patients. After discussions with...
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