BC Innovations | Jan 15, 2015
Distillery Therapeutics

Therapeutics: Epidermal growth factor receptor 2 (EGFR2; HER2; ErbB2; neu)

Cancer INDICATION: Brain cancer Mouse and cell culture studies suggest ANG4043 , a conjugate of the brain-penetrant peptide angiopep-2 and an anti- HER2 mAb, could help treat brain cancer. In mice with HER2-positive brain tumors, IV...
BC Week In Review | Dec 15, 2014
Clinical News

Angiochem preclinical data

In mice bearing intracranial HER2-positive tumors, twice-weekly 15 mg/kg IV ANG4043 significantly improved median overall survival (OS) vs. vehicle-treated controls (80 vs. 45 days, p=0.0003). Data were published in Molecular Cancer Therapeutics. ANG4043 consists of...
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