08:00 , Nov 6, 2014 |  BC Innovations  |  Tools & Techniques

AD goes 3D

A 3D cell-based model that encapsulates the two hallmark features of Alzheimer's disease-neurofibrillary tangles and b-amyloid plaques-has been created by a team at Massachusetts General Hospital to help screen compounds for the disease. 1 Although...
08:00 , Feb 26, 2009 |  BC Innovations  |  Targets & Mechanisms

New home for BDNF

BDNF 's clinical track record has been less than stellar and includes a Phase III failure in amyotrophic lateral sclerosis. A group at the University of California, San Diego attributes past failures to ineffective drug...